Commercial Name


Generic Name

Amoxicillin Trihydrate BP


Mymoxcil® 250 mg Capsule: Each Capsule contains Amoxicillin Trihydrate BP equivalent to 250 mg Amoxicillin BP.
Mymoxcil® 500 mg Capsule: Each Capsule contains Amoxicillin Trihydrate BP equivalent to 500 mg Amoxicillin BP.
Mymoxcil®¬ Dry Powder for Suspension: When reconstituted, each 5ml suspension contains Amoxicillin Trihydrate BP equivalent to amoxicillin 125 mg.


Mymoxcil® (Amoxicillin ) is and azalide antibiotic, subclass of the macrolide class of antibiotics. Mymoxcil® (Amoxicillin ) acts by binding to the 50S ribosomal subunit of susceptible organisms and thus interferes with microbial protein synthesis. Mymoxcil® demonstrated activity in vitro, against a wide range of Gram positive and Gram-negative bacteria including: Staphylococcus aureus, Streptococcus pneumonia, Streptococcus pyogenes (Group A) and other Streptococcus species; Haemophilus influenza and parainfluenzae; Moraxella catarrhalis; anaerobes including bacteroides fragilis, Escherichia coli, Bordetella pertussis, Bordetella parapertussis, Borrelia burgdorferi, Haemophilus ducreyi, Neisseria gonorrhoeae and chlamydia trachomatis. Mymoxcil® also demonstrates activity in vitro against Legionella pneumophila, Mycoplasma pneumonia and hominis; Campylobacter spp. Toxoplasma gondii and Treponema pallidum.


It is bactericidal antibiotic of the Amino penicillin group which is effective against a wide range of Gram-Positive and Gram-Negative organisms i.e., for the treatment of infections due to respiratory and urinary tract infections due to sensitive organisms. It is also used in sinusitis, tonsillitis, pharyngitis, laryngitis, acute and chronic bronchitis, pneumonia.

Dosage & Administration

Route of administration: Oral
Adults and children weighing over 40 kg: 250 mg every 8 hours, increasing to 500 mg every 8 hours in severe infections
Children weighing < 40 kg: The daily dosage for children is 40 – 90 mg/kg/day in two to three divided doses* (not exceeding 3 g/day) depending on the indication, severity of the disease and the susceptibility of the pathogen (see special dosage recommendations below and sections 4.4, 5.1 and 5.2).
Direction for Reconstitution (Syrup) :
Shake the bottle to disperse the powder. Add with spoon provided 14 teaspoonfuls (70 mL) of boiled and cooled water to powder.
Shake vigorously until a homogeneous liquid is formed.
The reconstituted syrup should be stored in a cool place preferably in refrigerator and use within 7 days of preparation. Shake the bottle well before use.


Amoxicillin should not be given to patients with hypersensitivity to penicillins. Attention should be given to the possibility of cross-sensitivity with other beta-lactam antibiotics eg: cephalosporins.
It should not be given to patients with infectious mononucleosis (glandular fever) since they are especially susceptible to amoxicillin-induced skin rashes.


Serious and occasionally fatal hypersensitivity (anaphylactoid) reactions have been reported in patients with penicillin therapy. These reactions are most likely in those with a history of hypersensitivity to beta-lactam antibiotics.
Amoxicillin should be used with caution in those with impaired renal function and dose reduction may be necessary in severe impairment.

Side Effect

Mymoxcil® (Amoxicillin) exhibits interaction with hormonal contraceptives, oral anticoagulants, allopurinol, chloramphenicol and gentamycin sulphate.
Use in pregnancy:
There is no evidence that amoxicillin is teratogenic or foetotoxic in humans. The product has been in extensive clinical use for many years and is considered safe in pregnancy.


Problems of overdosage with amoxicillin are unlikely to occur. If encountered, gastrointestinal effects such as nausea, vomiting and diarrhoea may be evident and should be treated symptomatically.
Overdose: there are no data on over dosage with Amoxicillin. Typical symptoms of over dosage with macrolide antibiotics include hearing loss, severe nausea, vomiting and diarrhea. Gastric lavage and supportive measure are indicated.


Mymoxcil® (Amoxicillin ) capsules and dry powder for suspension should be stored at room temperature (below 300 C). any unused portion of reconstituted Mymoxcil® suspension should be discarded after 5 days.

Pack Size

Mymoxcil® 250 Capsule: Box containing 2X3’s Capsule in Alu-Alu blister pack
Mymoxcil® 500 Capsule: Box cantaining 2×3’s Capsule in Alu-Alu blister pack
Mymoxcil® Suspension: Each sealed cap amber glass bottle contains dry powder for reconstituting 15 ml Suspension.
Keep in a cool dry place and protect from light.
Keep out of the reach of children.

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